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Bretazenil
Bretazenil is a partial agonist of GABA (gamma-aminobutyric acid) receptors, widely distributed in the brain. This pharmaceutical belongs to the class of benzodiazepines and in its structure and function resembles drugs such as alprazolam, diazepam and lorazepam. However, Bretazenil differs from them in its unique mechanism of action. As a partial agonist, it has anxiolytic,…
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Description
Bretazenil is a partial agonist of GABA (gamma-aminobutyric acid) receptors, widely distributed in the brain. This pharmaceutical belongs to the class of benzodiazepines and in its structure and function resembles drugs such as alprazolam, diazepam and lorazepam. However, Bretazenil differs from them in its unique mechanism of action. As a partial agonist, it has anxiolytic, anticonvulsant, sedative and muscle relaxant properties similar to full-fledged benzodiazepine agonists, but with a lower risk of undesirable effects and dependence.
Bretazenil is used as an important research tool that provides valuable information about the functioning and possible disorders of the GABA system in various neurological and psychiatric disorders. Its high affinity and effectiveness for GABA receptors make it possible to study in detail the features of this neurotransmitter system.
Improper use of Bretazenil for recreational purposes is strongly discouraged and illegal, as the full range of its potential health effects has not yet been fully studied. In addition, misuse can have serious legal consequences.
Technical Information:
Product Name: Bretazenil
Synonyms: Ro 16-6028
CAS: 84379-13-5
IUPAC: (13aS)-8-
Molecular Formula: C19H20BrN3O3
Molecular Weight: 418.3 g/mol
Purity: 98.0 % min.
Formulations: A crystalline solid
Solubility:
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 20 mg/ml
- PBS (pH 7.2): Partially soluble
InChI: InChI=1S/C19H20BrN3O3/c1-19(2,3)26-18(25)15-16-13-8-5-9-22(13)17(24)14-11(20)6-4-7-12(14)23(16)10-21-15/h4,6-7,10,13H,5,8-9H2,1-3H3/t13-/m0/s1
InChIKey: LWUDDYHYYNNIQI-ZDUSSCGKSA-N
SMILES: CC(C)(C)OC(=O)C1=C2[C@@H]3CCCN3C(=O)C4=C(N2C=N1)C=CC=C4Br
Storage: -20°C
Stability: ≥ 4 years
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