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2-Methyl-PiHP (2-Me-PiHP) is a compound from the group of pyrrolidine stimulants, known for its pronounced effect on the dopamine and norepinephrine systems. Due to methyl substitution, which improves its pharmacological properties, 2-Me-PiHP provides rapid stimulation, increased cognitive abilities, and improved concentration. Studies confirm its ability to increase the level of energy, attention and sociability, and…
2-Methyl-PiHP (2-Me-PiHP) is a compound from the group of pyrrolidine stimulants, known for its pronounced effect on the dopamine and norepinephrine systems. Due to methyl substitution, which improves its pharmacological properties, 2-Me-PiHP provides rapid stimulation, increased cognitive abilities, and improved concentration. Studies confirm its ability to increase the level of energy, attention and sociability, and also provide valuable information about the mechanisms of interaction with the monoaminergic system.
This compound is especially important for laboratory studies, as its effect reaches its peak after 1-2 hours and lasts up to 6 hours. To obtain reliable results, it is important to follow accurate dosing and measures to reduce potential risks.
Chemical structure and properties
2-Me-PiHP has high lipophilicity, which allows it to effectively cross the blood-brain barrier. Its pharmacodynamics is based on its ability to bind to monoamine transporters, including dopamine (DAT) and norepinephrine (NET), which leads to inhibition of their reuptake and an increase in the level of neurotransmitters in the synaptic cleft.
Pharmacological effects
Based on laboratory studies and individual reviews, 2-Me-PiHP exhibits the following effects:
Stimulation: increased physical and mental activity, increased alertness and concentration.
Euphoria: a short-term mood boost and a sense of well-being.
Social activity: increased confidence and talkativeness.
Cognitive enhancement: improving short-term memory and problem-solving ability.
The effect occurs 15-30 minutes after administration, reaching a maximum after 1-2 hours. The total duration of action is 4-6 hours, depending on the dosage and metabolic characteristics of the body.
Dosage and precautions
Attention! All information is provided solely for research purposes. Human consumption is not recommended.
Dosage
Minimum dose: 5-10 mg
Light dose: 10-20 mg
Usual dose: 20-30 mg
High dose: 30-40 mg
Due to the high efficacy, it is recommended to start with minimal doses to avoid adverse reactions. It is important to use accurate measuring equipment in laboratory experiments.
Side effects
If the dosage is exceeded or prolonged exposure, the following negative reactions may occur:
Psychological: anxiety, paranoia, increased irritability.
Physiological: increased heart rate, increased blood pressure, increased sweating.
Neurological: headache, dizziness, sleep disorders.
Prolonged use can lead to addiction, tolerance, and neurotoxicity.
Risk mitigation measures
The following recommendations should be considered for safe research::
Avoid combination with other stimulants and depressants to prevent unwanted interactions.
Use accurate dosing using calibrated scales.
Conduct research under controlled conditions, excluding random factors.
Provide sufficient moisture to prevent dehydration.
Observe the intervals between experiments, avoiding repeated exposure in a short time.
2-Me-PiHP is an advanced compound that opens up new possibilities in the study of CNS stimulation and the mechanisms of monoaminergic regulation. With a responsible approach, it can provide valuable information for further pharmacological research.
Legal status
2–Me–PiHP is not controlled in many countries. It is a derivative of a-PiHP and may be controlled by law in some countries where analogues of these substances are under control.
Technical Information:
Product Name: 2–Me–PiHP
Synonyms: 3,4-Methylenedioxy-α-Pyrrolidinoisohexanophenone,3,4-Methylenedioxy PiHP, 4-Ethyl-alpha-Pyrrolidinovalerophenone
CAS: 24622-58-0
IUPAC: 4-methyl-2-(pyrrolidin-1-yl)-1-(o-tolyl)pentan-1-one hydrochloride
Molecular Formula: C17H26ClNO
Molecular Weight: 295.85 g/mol
Purity: 98.0 % min.
Formulations: A crystalline solid
Solubility:
Stability: ≥ 4 years
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