Spirochlorphine

Description

Spirochlorphine (R6890) is a powerful therapeutic agent with pronounced anxiolytic, sedative and analgesic properties. Originally developed to treat anxiety disorders and sleep disorders, it has also proven effective in relieving pain, especially in patients with chronic pain and increased anxiety. Due to its complex effect on neurotransmitter systems, Spirochlorphine helps to alleviate both psychological stress and physical discomfort.

Mechanism of action: Spirochlorphine acts as a modulator of mu opioid receptor, GABA receptors, enhancing the inhibitory effect of the brain’s main calming neurotransmitter, GABA. This leads to a decrease in nervous excitability, promotes relaxation, reduces anxiety and improves sleep quality.

Additionally, the drug acts on opioid receptors, mimicking endogenous analgesics, which leads to a pronounced analgesic effect. This dual effect makes Spirochlorfin an effective treatment for patients experiencing both physical and emotional pain.

Therapeutic use:

Anxiety Disorders – helps with generalized anxiety, panic attacks, and social anxiety.

Insomnia – improves falling asleep and supports prolonged sleep.

Analgesia is effective for chronic pain, neuropathy, and postoperative discomfort.

Treatment of chronic pain is especially useful for conditions accompanied by anxiety or depression, such as fibromyalgia and arthritis.

Effectiveness: The analgesic and sedative effect of Spirochlorphine is felt 30-60 minutes after ingestion. Patients report reduced anxiety, improved mood, and significant pain relief. Due to its combined effect on GABA and opioid receptors, the drug provides comprehensive treatment.

Possible side effects:

Drowsiness and sedation – it is recommended to avoid driving and working with mechanisms.

Dizziness – especially with sudden changes in body position.

Gastrointestinal disorders – nausea and constipation are possible.

The risk of dependence is that tolerance may develop with prolonged use.

Paradoxical reactions – some patients may experience increased anxiety or irritability.

Interactions with other drugs: Spirochlorphine should not be combined with alcohol, benzodiazepines or other substances that depress the central nervous system, as this can enhance its sedative effect and lead to dangerous consequences. It should also be carefully combined with traditional opioids and antidepressants.

Contraindications:

Diseases of the respiratory system – not recommended for sleep apnea or COPD.

A history of substance abuse is an increased risk of addiction.

Pregnancy and lactation – insufficient data on safety for the fetus and infant.

Safety measures: To minimize the risks, Spirochlorphine should be used strictly as prescribed by a doctor. If necessary, the dose should be reduced gradually to avoid withdrawal symptoms.

Conclusion: Spirochlorphine is an innovative remedy that provides comprehensive relief of anxiety, insomnia and pain. Its balanced effects on GABA and opioid receptors make it a powerful but relatively safe option for patients experiencing both emotional and physical suffering. Responsible use under medical supervision allows you to get the maximum benefit from the drug with minimal risk.

Regulatory status:

It is not regulated in many countries as a research substance.

Technical Information:

Product Name:  Spirochlorphine

Synonyms: R6890

CAS: 3222-88-6

IUPAC: 8-[1-(4-chlorophenyl)ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one

Molecular Formula: C₂₁H₂₄ClN₃O

Molecular Weight:  369.9 g/mol

Purity:  98.0 % min.

Formulations: A solid

SMILES: CC(C1=CC=C(C=C1)Cl)N2CCC3(CC2)C(=O)NCN3C4=CC=CC=C4

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