Pynazolam

Pynazolam is a sedative of the benzodiazepine class, a derivative of triazolobenzodiazepine, which has powerful sedative and hypnotic effects. For the first time, information about this drug became known in the 1970s, by a group led by Leo Sternbach. This drug has never been used in medicine and has not been marketed. You can buy…

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Description

Pynazolam is a sedative of the benzodiazepine class, a derivative of triazolobenzodiazepine, which has powerful sedative and hypnotic effects.
For the first time, information about this drug became known in the 1970s, by a group led by Leo Sternbach. This drug has never been used in medicine and has not been marketed.

Chemical properties

Pynazolam is a derivative of triazolobenzodiazepine, which differ from other benzodiazepines by having an additional triazole ring connected to the diazepine ring.

Pharmacological properties

Rodent studies have shown that Pynazolam acts as a powerful hypnotic and relaxing agent.

Legal status

Pynazolam is a research drug with unclear legal status.

Technical Information:

Product Name:  Pynazolam

Synonyms: 8-nitro-1-methyl-6-(2-pyridyl)-4H-s-triazolo(4,3-a)(1,4)benzodiazepine

CAS: 2034366-97-5

IUPAC: 1-methyl-8-nitro-6-pyridin-2-yl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine

Molecular Formula: C16H12N6O2

Molecular Weight:  320.31 g/mol

Purity:  98.0 % min.

Formulations: A crystalline solid

Solubility:

  • DMF: 30 mg/ml
  • DMSO: 30 mg/ml
  • Ethanol: 20 mg/ml
  • PBS (pH 7.2): Partially soluble
InChI: InChI=1S/C16H12N6O2/c1-10-19-20-15-9-18-16(13-4-2-3-7-17-13)12-8-11(22(23)24)5-6-14(12)21(10)15/h2-8H,9H2,1H3
InChIKey: TULLJLNDPPOHKC-UHFFFAOYSA-N

SMILES: CC1=NN=C2N1C3=C(C=C(C=C3)[N+](=O)[O-])C(=NC2)C4=CC=CC=N4

Storage: -20°C

Stability: ≥ 4 years

Not for human consumption

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