MXiPr

MXiPr (3-MeO-2′-Oxo-PCiPr, Methoxisopropamine, Isopropyloxetamine, Isopropyxetamine) is a dissociative drug of the arylcyclohexylamine class acting as an NMDA receptor antagonist. This designer drug first appeared in 2020 as a research substance developed as a replacement for MXE. Studies in mice have shown that MXiPr acts as an NMDA receptor antagonist and is also a serotonin reuptake…

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Description

MXiPr (3-MeO-2′-Oxo-PCiPr, Methoxisopropamine, Isopropyloxetamine, Isopropyxetamine) is a dissociative drug of the arylcyclohexylamine class acting as an NMDA receptor antagonist.
This designer drug first appeared in 2020 as a research substance developed as a replacement for MXE.

Chemistry

MXiPr is a derivative of drugs such as ketamine and methoxetamine.
MXiPr contains an isopropyl group on the nitrogen atom of the molecule and an oxygen atom at the 2′ position of the cyclohexyl ring, as well as a methoxy group at the 3 position of the phenyl ring.

Pharmacology

The data on the toxicological and faramcological properties of MXiPr are incomplete.
Studies in mice have shown that MXiPr acts as an NMDA receptor antagonist and is also a serotonin reuptake inhibitor. This drug causes dissociative, sedative and euphoric effects.
Dosage:
Threshold 5 mg
Light 10 – 20 mg
Common 20 – 40 mg
Strong 40 – 60 mg
Heavy 60 mg +
Exposure time:
Total 2 – 5 hours
Onset 20 – 60 minutes
After effects 4 – 48 hours

Legal status

DE: NpSG (Industrial and scientific use only)
UK: Class B
CA: Schedule I
Hungary: Not legal

Technical Information:

Product Name:  MXiPr

Synonyms: 3-MeO-2′-Oxo-PCiPr, Methoxisopropamine, Isopropyloxetamine, Isopropyxetamine

CAS: 2666932-55-2

IUPAC: 2-(3-methoxyphenyl)-2-(propan-2-ylamino)cyclohexan-1-one

2-(isopropylamino)-2-(3-methoxyphenyl)cyclohexan-1-one

Molecular Formula: C16H23NO2

Molecular Weight:  261.36 g/mol

Purity:  98.0 % min.

Formulations: A crystalline solid

Solubility:

DMF: 20 mg/ml

 

MSO: 10 mg/ml

Ethanol: 20 mg/ml

PBS (pH 7.2): 2 mg/ml

InChI: InChI=1S/C16H23NO2/c1-12(2)17-16(10-5-4-9-15(16)18)13-7-6-8-14(11-13)19-3/h6-8,11-12,17H,4-5,9-10H2,1-3H3
InChIKey: FTQIVDGNGXPEKP-UHFFFAOYSA-N

SMILES: CC(C)NC1(CCCCC1=O)C2=CC(=CC=C2)OC

Storage: -20°C

Stability: ≥ 4 years

Not for human consumption

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