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MXiPr (3-MeO-2′-Oxo-PCiPr, Methoxisopropamine, Isopropyloxetamine, Isopropyxetamine) is a dissociative drug of the arylcyclohexylamine class acting as an NMDA receptor antagonist. This designer drug first appeared in 2020 as a research substance developed as a replacement for MXE. Studies in mice have shown that MXiPr acts as an NMDA receptor antagonist and is also a serotonin reuptake…
MXiPr (3-MeO-2′-Oxo-PCiPr, Methoxisopropamine, Isopropyloxetamine, Isopropyxetamine) is a dissociative drug of the arylcyclohexylamine class acting as an NMDA receptor antagonist.
This designer drug first appeared in 2020 as a research substance developed as a replacement for MXE.
Chemistry
MXiPr is a derivative of drugs such as ketamine and methoxetamine.
MXiPr contains an isopropyl group on the nitrogen atom of the molecule and an oxygen atom at the 2′ position of the cyclohexyl ring, as well as a methoxy group at the 3 position of the phenyl ring.
Pharmacology
The data on the toxicological and faramcological properties of MXiPr are incomplete.
Studies in mice have shown that MXiPr acts as an NMDA receptor antagonist and is also a serotonin reuptake inhibitor. This drug causes dissociative, sedative and euphoric effects.
Dosage:
Threshold 5 mg
Light 10 – 20 mg
Common 20 – 40 mg
Strong 40 – 60 mg
Heavy 60 mg +
Exposure time:
Total 2 – 5 hours
Onset 20 – 60 minutes
After effects 4 – 48 hours
Legal status
DE: NpSG (Industrial and scientific use only)
UK: Class B
CA: Schedule I
Hungary: Not legal
Technical Information:
Product Name: MXiPr
Synonyms: 3-MeO-2′-Oxo-PCiPr, Methoxisopropamine, Isopropyloxetamine, Isopropyxetamine
CAS: 2666932-55-2
IUPAC: 2-(3-methoxyphenyl)-2-(propan-2-ylamino)cyclohexan-1-one
2-(isopropylamino)-2-(3-methoxyphenyl)cyclohexan-1-one
Molecular Formula: C16H23NO2
Molecular Weight: 261.36 g/mol
Purity: 98.0 % min.
Formulations: A crystalline solid
Solubility:
DMF: 20 mg/ml
MSO: 10 mg/ml
Ethanol: 20 mg/ml
PBS (pH 7.2): 2 mg/ml
SMILES: CC(C)NC1(CCCCC1=O)C2=CC(=CC=C2)OC
Stability: ≥ 4 years
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